When self-help author Dr. Burke Ryan arrives in Seattle to teach a sold-out seminar, he unexpectedly meets florist Eloise Chandler, the one person who might be able to help him help himself. But will two people who have met the right person at exactly the wrong time be able to give love another chance? They'll find that sometimes when you least expect it ... love happens.

Donald and Isabelle have a form of autism called Asperger's Syndrome. Donald, a good-natured but hapless cab driver has a knack for numbers. He falls head over heals in love with the beautiful but complex Isabelle when she joins the autism support group he leads.

Hazel and Gus are two extraordinary teenagers who share an acerbic wit, a disdain for the conventional, and a love that sweeps them on an unforgettable journey. Their relationship is all the more miraculous, given that they met and fell in love at a cancer support group.

In season two, the onetime outsider finds himself fully a part of this eclectic group of misfits all the while struggling with the knowledge that life exists beyond our world. Special Agent Alex Foster, a smart, dedicated FBI investigator who's on a mission to Beacon to track down fugitive CEO Jonathan Walsh for white-collar crime, but soon learns he harbors even greater secrets. The arrival of a new alien management on the spaceship complicates matters....

Carl Allen signs up for a self-help program based on one simple principle: say yes to everything ... and anything. Unleashing the power of 'yes' transforms Carl's life in amazing and unexpected ways, but he soon discovers that embracing every opportunity might just become too much of a good thing.